❗ Problem: “Why Do I Keep Getting Surprised by Outcomes?” Have you ever made a decision that seemed smart, only to watch it collapse because you didn’t anticipate how someone else would react? This is what happens when you don’t think sequentially — when you make your move without considering the moves that follow. …
🔑 Key Takeaways 🎯 The Punchline Think of MODR as your method’s “comfort zone” — a scientifically proven range where it works reliably, even if small changes happen. In traditional method development, you pick one set of conditions. You validate that.Then you hope everything else holds steady. In AQbD, you design a region, …
❗ Why Doesn’t Anyone Make the First Move? Ever wonder why: It’s not always laziness, fear, or indifference.Often, it’s a strategic freeze — each person is waiting for the other to change first. This is a classic Nash Equilibrium: A situation where no one can improve their outcome by acting alone, so everyone stays stuck, even …
The Problem: We Hurt Ourselves by Trying to Protect Ourselves Have you ever trusted someone — only to regret it?Or held back because you feared the other person might betray you first? In those moments, you’re not just reacting emotionally.You’re likely stuck in what’s called a Prisoner’s Dilemma — one of the …
When working in regulated labs, you often hear phrases like: “Flow rate is a CQA…” “LOD is a CMP…” At first, those terms might sound correct. But in Analytical Quality by Design (AQbD), confusing Critical Quality Attributes (CQAs) with Critical Method Parameters (CMPs) is a common mistake. And it can be a costly …
Key Takeaways What This Post Will Cover The Punchline: If You Don’t Know the Target, You Can’t Hit It In analytical labs, too often, we jump straight into tweaking columns, mobile phases, and pH conditions. But if you don’t define what your method is supposed to achieve, you’re aiming at a …
Learn the crucial difference between competing for survival and growing together — and why it changes everything. Have you ever been in a situation where it felt like someone had to lose for you to win?Or other times when everyone could succeed — but competition ruined it anyway? If you don’t know …
Understand the hidden games people play — and how to stay three moves ahead in business, relationships, and life. Have you ever made a decision that seemed smart in the moment — only to realize later it actually made things worse?Or watched two people fight so hard to “win” that …
Key Takeaways What This Post Will Cover 🎯 The Punchline: If You Don’t Know the Target, You Can’t Hit It In analytical labs, too often, we jump straight into tweaking columns, mobile phases, and pH conditions. But if you don’t define what your method is supposed to achieve, you’re aiming at a …
Key Takeaways What This Post Will Cover 🎯 The Punchline: Old-School Method Development Leaves Too Much to Chance In most labs—even good ones—analytical methods are developed like recipes passed down in a kitchen.Maybe it works. Maybe it doesn’t. But no one really knows why. Without structure, most methods: That’s where Analytical Quality by …
